The continuing consumption of a bundle containing blackcurrant juice and grape juice changes the value relationship between the two juices (left): gradually less blackcurrant juice is given up to gain the same amount of grape juice (coloured dots), as shown by progressively flattening choice indifference curves (coloured curves). Thus, grape juice has lost value relative to blackcurrant juice, indicating satiety for grape juice relative to blackcurrant juice. The neuronal responses to the bundle stimuli follow the flattened indifference curves (right), as shown by the responses with sated grape juice (bottom right). Thus, the reward signal in OFC neurons reflects satiety-induced value changes of individual choice options. View the report here (Pastor-Bernier et al. 2021).